Fatigue Resource Directory: Countermeasures



This document is intended as a resource directory and was compiled from input provided by a wide range of sources.
The information provided in this Directory has not been evaluated for its accuracy or effectiveness.
Therefore, inclusion in this Directory does not imply endorsement by the NTSB or NASA.
FReDi Contents | Government Activities | Industry Activities | Public Interest Groups | Scientific Information | Referral Form | Search

Physiological
Bright Light
Naps
Naps
Strategic Naps
Pharmacology
Caffeine
Caffeine
Melatonin
Sleeping Pills
Schedules/Behavioral
Active/Passive Vigilance
Audiogenic» Sleep Training System
Improved Work Schedule Systems
Technology
On-line Vigilance Monitoring with the ñNightcapî
Pilot Guard System
Rumble Strips

Countermeasures: Physiological

Bright Light

Contact information:
Sleep Medicine and Research Center
James K. Walsh, Ph.D., Director
St. Luke's Hospital
232 S. Woods Mill Rd.
Chesterfield, MO 63017
(314) 851-6030
(314) 851-6025

Description:

Representative publications:

Most recent publications:
Thessing, V et al. Two-and four-hour bright light exposures differentially affect sleepiness and performance the subsequent night. Sleep, 1994, 17(2), 140-145.

Naps

Contact information:
VA Medical Center (127)
Michael H. Bonnet, Ph.D.
4100 West Third St.
Dayton, OH 45428
(513) 267-3910
(513) 267-5317 fax
E-mail: bonnet.michael@dayton.va.gov

Description:
Naps taken prior to nocturnal work periods can significantly improve alertness and performance during the third shift. Naps taken prior to the third shift may be more beneficial than naps taken during the third shift.

Representative publications:
Bonnet, M.H. Dealing with shiftwork: Physical fitness, temperature, and napping. Work and Stress, 1990, 4, 261-274.

Bonnet, M.B. The effect of varying prophylactic naps on performance, alertness and mood throughout a 52-hour continuous operation. Sleep, 1991, 14, 307-315.

Bonnet, M.H. & Arand, D.L. Consolidated and distributed nap schedules and performance. Journal of Sleep Research, 1995, 4, 71-77.

Most recent publications:
Bonnet, M.H. & Arand, D.L. The impact of naps and caffeine on extended nocturnal performance. Physiology & Behavior, 1994, 56, 103-109.

Bonnet, M.H. Gomez, S. Wirth, O & Arand, D.L. The use of caffeine versus prophylactic naps in sustained performance. Sleep, 1995, 18, 97-104.

Bonnet, M.H. & Arand, D.L. Consolidated and distributed nap schedules and performance. Journal of Sleep Research, 1995, 4, 71-77.

Naps

Contact information:
Sleep Medicine and Research Center
James K. Walsh, Ph.D., Director
St. Luke's Hospital
232 S. Woods Mill Rd.
Chesterfield, MO 63017
(314) 851-6030
(314) 851-6025

Description:

Representative publications:
Schweitzer, P.K., Muehlbach, M.J., and Walsh, J.K. Countermeasures for nightwork performance deficits: The effect of napping or caffeine on continuous performance at night. Work & Stress, 1992, 6, 355-365.

Sugerman, J.L. and Walsh, J.K. Physiological sleep tendency and ability to maintain alertness at night. Sleep, 1989, 12, 106-112.

Most recent publications:

Strategic Naps

Contact information:
Mark R. Rosekind, Ph.D.
Donna L. Miller
Fatigue Countermeasures Program
NASA Ames Research Center
Mail Stop 262-4
Moffett Field, CA 94035-1000
(415) 604-6435
(415) 604-2177 fax

Description:
This study examined the effectiveness of a planned cockpit rest period to improve alertness and performance in long-haul flight operations. Co-sponsored and sanctioned by the FAA, it involved the voluntary participation of two commercial airlines. The results demonstrated that the brief inflight nap was associated with improved performance and physiological alertness compared to a no-rest group. The FAA has developed regulatory materials for implementing planned cockpit rest that is currently under consideration.

Representative publications:
Rosekind, M.R., Graeber, R, Dinges, D.F., Connell, L.J., Rountree, M.S., and Gillen, K. (1994). Crew Factors in Flight Operations IX: Effects of Planned Cockpit Rest on Crew Performance and Alertness in Long-Haul Operations. (NASA Technical Memorandum No. 108839). Moffett Field, CA: NASA Ames Research Center.

Most recent publications:
Rosekind, M.R., Smith, R.M., Miller, D.L., Co, E.L., Gregory, K.B., Webbon, L.L., Gander, P.H., and Lebacqz, J.V. (in press). Alertness management: strategic naps in operational settings. J. Sleep Res. 4, (Suppl. 2).

Countermeasures: Pharmacology

Caffeine

Contact information:
VA Medical Center (127)
Michael H. Bonnet, Ph.D.
4100 West Third St.
Dayton, OH 45428
(513) 267-3910
(513) 267-5317 fax
E-mail: bonnet.michael@dayton.va.gov

Description:
Caffeine, given in doses ranging from 150-400 mg either by itself or following naps helps to maintain alertness and performance for at least the first 24 hours of total sleep deprivation.

Representative publications:
Bonnet, M.H. Gomez, S. Wirth, O & Arand, D.L. The use of caffeine versus prophylactic naps in sustained performance. Sleep, 1995, 18, 97-104.

Bonnet, M.H. & Arand, D.L. The impact of naps and caffeine on extended nocturnal performance. Physiology & Behavior, 1994, 56, 103-109.

Bonnet, M.H. & Arand, D.L. The use of prophylactic naps and caffeine to maintain performance during a continuous operation. Ergonomics, 1994, 37, 1009-1020.

Most recent publications:

Caffeine

Contact information:
Sleep Medicine and Research Center
James K. Walsh, Ph.D., Director
St. Luke's Hospital
232 S. Woods Mill Rd.
Chesterfield, MO 63017
(314) 851-6030
(314) 851-6025

Description:

Representative publications:
Schweitzer, P.K., Muehlbach, M.J., and Walsh, J.K. Countermeasures for nightwork performance deficits: The effect of napping or caffeine on continuous performance at night. Work & Stress, 1992, 6, 355-365.

Walsh, J.K. Using psychopharmacological aids to improve waking function and sleep while working nights. Work and Stress 1990, 4(3), 237-243.

Most recent publications:
Muehlbach, M.J., and Walsh, J.K. The effects of caffeine on simulated night shift work and subsequent daytime sleep. Sleep, 1995, 18, 22-29.

Melatonin

Contact information:
Robert L. Sack, M.D.
Clinical Director, Sleep and Mood Disorders Laboratory
Oregon Health Sciences University
Mail Code L-469
Portland, OR 97201
(503) 494-6577
(503) 494-5329 fax
E-mail: sackr@ohsu.edu

Description:
Melatonin is a hormone that is normally produced by the pineal gland at night. Recent research indicates that it may be able to combat fatigue by several mechanisms.

1) Exogenous melatonin administration is able to "reset" the circadian clock. Depending on the time of day of the administration, it can shift circadian rhythms earlier or later; thus it may be able align the peak of the endogenous alertness rhythm with the time of greatest performance demand; likewise it may be able to align the sleep-propensity rhythm with the preferred time for sleep, thereby improving sleep and awake-time alertness. 2) Melatonin may have a direct sleep-promoting action that would be especially useful in allowing people to sleep at atypical times. These two proposed actions of melatonin may be synergistic; for example, it might reduce fatigue related to "jet lag" by promoting circadian rhythm readjustment as well as improving sleep after arrival at the new destination.

Representative publications:
Reman J, Armstron S and Ng KT. Free-running activity rhythms in the rat: entrainment by melatonin. Science 1983; 219:1089-1091.

Arendt J, Aldhous M, English J, Marks V, Arendt JH, Marks M and Folkard S. Some effects of jet-lag and their alleviation by melatonin. Ergonomics 1987; 30:1379-1393.

Dahlitz M, Alverez B, Vignau J, English J, Arendt J and Parkes JD. Delayed sleep phase syndrome response to melatonin. Lancet 1991; 337:1121-1124.

Lewy A, Ahmed S, Latham-Jackson J and Sack R. Melatonin shifts human circadian rhythms according to a phase-response curve. Chronobiol. Internat. 1992; 9:380-392.

Most recent publications:
Sack RL, Blood ML and Lewy AJ. Melatonin administration promotes circadian adaptation to night-shift work. Sleep Research 1994; 23:509.

Tzischinsky O and Lavie P. Melatonin possesses time-dependent hypnotic effects. Sleep 1994; 17:638-645.

Hughes RJ, Badia P, French J, Santiago L and Plenzler S. Melatonin induced changes in body temperature and daytime sleep. Sleep Res. 1994; 23:496.

Sleeping Pills

Contact information:
Sleep Medicine and Research Center
James K. Walsh, Ph.D., Director
St. Luke's Hospital
232 S. Woods Mill Rd.
Chesterfield, MO 63017
(314) 851-6030
(314) 851-6025

Description:

Representative publications:
Schweitzer, P.K. et al. Effects of estazolam and triazolam on transient insomnia associated with phase-shifted sleep. Human Psychopharmacology, 1991, 6, 99-107.

Walsh, J.K. et al. Sleepiness/alertness on a simulated night shift following sleep at home with triazolam. Sleep, 1991, 14, 140-146.

Walsh, J.K. et al. Physiological sleep tendency on a simulated night shift: Adaptation and effects of triazolam. Sleep, 1988, 11, 251-264.

Most recent publications:

Countermeasures: Schedules/Behavioral

Active/Passive Vigilance

Contact information:
Airbus Industrie
Jean-Jacques Speyer
Operational Evaluation & Communication Manager
AI/ST-F#
1, Rond Point Maurice Bellonte
31707 Blagnac Cedex / France
(33) 61.93.30.03
(33) 61.93.29.68 fax
530526F Telex

Description:
This recommendation was developed under a program with DGAC involving Air France, UTA, Aeromaritime, Sabena, and Northwest. Some 156 fights were performed on long-range north-south, east-west airline routes on B747-400, B767, A310, A320, and A340. A scheme of active/passive vigilance was developed by the joint team of the Laboratory of Applied Anthropology (LAA) and the Laboratory of Physiology of Adaptions (LPA) and Airbus Industrie.

Under this scheme, the active pilot would concentrate on maintaining interaction with the flight management and aircraft monitoring systems and perform en-route navigational and communications requirements. The passive pilot would take a rest period spanning 20 to 40 minutes, where he could oversee the operation and/or indulge in relation or remote activities--such as eating, reading, napping. Adequate attention for the efficient and safe progress of the flight will thus be maintained by alternating the active and passive pilots on a periodic basis as mutually agreed, with both pilots being active when operationally required. The suggested time periods should definitely not be longer, as it was demonstrated that prolonged "lonesomeness" (next to a napping fellow pilot) can induce underarousal and consequent lack of vigilance on the part of the active pilot. This scheme was successfully demonstrated on medical terms and implemented by means of the Pilot Guard System.

Representative publications:

Most recent publications:

Audiogenic Sleep Training System

Point of Contact:
Christopher Alsten, Ph.D.
Inner Health, Inc.
P.O. Box 1609
Idyllwild, CA 92549-1609
(909) 659-2997
(909) 659-6037 fax

Description:
Preliminary evaluation with a small sample of aircrew members showed significant objective (actigraphy) and subjective improvements in layover and in-flight sleep when using a proprietary "Sleep Training" System. An R&D effort is underway to refine the "Sleep Training" System and evaluate its effectiveness with a larger number of pilots, copilots, flight engineers and various USAF shiftworks using PSG/MSLTs as well as actigraphy and subjective measures.

Representative publications:
Alsten, C. Downey, R. III and Jackson, T. Preliminary Evaluation of a "Sleep Training" Program to Enhance the Quality and Quantity of Aircrew Sleep (Sleep Research 1995, in press).

Jackson, T. & Alsten, C. Replacement of Sedative-Hypnotics with a Multi-Modality, Tape Recorded Insomnia Treatment Program on a Locked Psychiatric Unit (Sleep Research 1995, in press).

Most recent publications:

Improved Work Schedule Systems

Point of Contact:
Prof. Donald I. Tepas
Ergonomics Laboratory
University of Connecticut, Storrs
406 Babbidge Rd.
Box U-20
Storrs, CN 06269-1020
(203) 486-5557
(203) 486-2760 fax

Description:

Over the years, many fatigue countermeasures have been proposed. To date, only one approach, improved work schedule systems, has proven efficacious long term effects. Improved work schedule systems recognize that cultural, social, individual and chronobiological factors must all be considered in the design of a work system. Our general approach to designing improved work schedule systems features voluntary and confidential worker and organization participation. We think that the formal quantitative evaluation of work schedule changes should be considered a mandatory action, since current knowledge levels make countermeasures more art than science. All evaluators have a clear professional obligation to disseminate their findings in peer-reviewed scientific journals.

Representative publications:
Tepas, D.I. and Monk, T.M. (1987) Work schedules. In: Handbook of Human Factors, G. Salvendy (Ed.). New York: John Wiley & Sons.

Tepas, D.I. and Mahan, R.P. (1989) The many meanings of sleep. Work and Stress, 3, 93-102.

Tepas, D.I., Armstrong, D.R., Carlson, M.L., Duchon, J, Gersten, A. and Lezotte, D.V. (1985) Changing industry to continuous operations: Different strokes for different plants. Behavioral Research Methods, Instruments & Computers, 17, 670-676.

Most recent publications:
Tepas, D.I. (1994) Technological innovation and the management of alertness and fatigue in the workplace. Human Performance, 7, 165-180.

Paley, M.J. and Tepas, D.I. (1994) Fatigue and the shiftworker: Firefighters working on a rotating shift schedule. Human Factors, 36, 269-284.

Tepas, D.I. (1993) Educational programs for shiftworkers, their families, and prospective shiftworkers. Ergonomics, 36, 199-209.

Countermeasures: Technology

On-line Vigilance Monitoring with the "Nightcap"

Contact information:
Harvard Medical School, Department of Psychiatry
Robert Stickgold, Ph.D., Instructor, Department of Psychiatry
Laboratory of Neurophysiology
Massachusetts Mental Health Center
74 Fenwood Road
Boston, MA 02155
(617) 734-1300 x316
(617) 734-7851 fax
E-mail: bstick@harvarda.harvard.edu

Description:
The Nightcap vigilance monitor uses an adhesive-backed piezoelectric film to monitor microscopic upper eye lid movements (ELMs). In a pilot study, EM frequency correlated with performance on various vigilance and cognitive tests over 40 hr of sleep deprivation, with Pearson correlation coefficients in the range of 0.75 to 0.82.

Representative publications:
Helfand R., P. Lavie, & J.A. Hobson (1986). REM/NREM discrimination via ocular and limb movement monitoring: correlation with polygraphic data and development of a REM state algorithm. Psychophysiology 23: 334-339.

Mamelak, A., & J.A. Hobson (1989). Nightcap: A home-based sleep-monitoring system. Sleep 12: 157-166.

Stickgold, R., E. Pace-Schott, & J.A. Hobson (1994). A new paradigm for dream research: Mentation reports following spontaneous arousals from REM and NREM sleep recorded in a home setting. Consciousness and Cognition 3: 16-29.

Most recent publications:
Ajilore, O., R. Stickgold, C.D. Rittenhouse & J.A. Hobson (1995). Nightcap: Laboratory and home-based evaluation of a portable sleep monitor. Psychophysiology 32: 92-98.

Pace-Schott, E.F., J. Kaji, R. Stickgold & J.A. Hobson (1995). Nightcap measurement of sleep quality in self-described good and poor sleepers. Sleep 17: 688-692.

Stickgold, R. & J.A. Hobson (1994) Home Monitoring of Sleep Onset and Sleep-Onset Mentation using the Nightcap. In Sleep Onset: Normal and abnormal processes (R. Ogilvie & J. Harsh, eds.), pp. 141-161. American Psychological Association Press: Washington.

Pilot Guard System

Contact information:
Page Aerospace Limited
Captain Adrian Elsey
Forge Lane, Sunbury-on-Thames, Middlesex,
TW16 6EO
United Kingdom
Phone: 44 1932 787661
Fax: 44 1932780349
E-mail: 100302.2276@compuserve.com

Description:
The Pilot Guard System (PGS) is a sophisticated timing device, incorporating pre-set periods of 5, 10, 25, and 45 minutes in PGS mode, and timing up to 45 minutes in timer mode. It can interface with the electronic systems on the aircraft fight deck to provide activity monitoring and provide a means for active/passive vigilance. The system allows one pilot to rest/nap during periods of low workload, as a means for countering fatigue and improving alertness.

Representative publications:
Page Aerospace Limited - Pilot Guard System, Background and System Operations

Most recent publications:

Rumble Strips

Contact information:
University of Maine
Per Garder
Associate Professor
Department of Civil and Environmental Engineering
5711 Boardman Hall
Orono, ME 04469-5711
(207) 581-2177
(207) 581-38888 fax
E-mail: garder@maine.maine.edu

Description:
Continuous shoulder rumble strips on the shoulder of a highway alert drivers that they have left the traveled roadway.

Representative publications:
Per Garder and John Alexander. "Fatigue Related Accidents and Continuous Rumble Strips." TRB Report 950132.

Per Garder. "Rumble Strips or Not Along Wide Shoulders Designated for Bicycle Traffic." TRB Preprint 950231.

Per Garder and John Alexander. "Shoulder Rumble Strips for Improving Safety on Rural Interstates. Final Report." Technical Paper 94-4, Maine DOT, Dec. 1994.

Most recent publications:

FReDi Contents | Countermeasures | Government Activities | Industry Activities | Public Interest Groups | Scientific Information | Referral Form | Search

Maintained by the Fatigue Countermeasures Group